Bipolar spectrum illness is found with the following features:
(1) Disturbances in emotional cognition
(2) The presence, on a cyclic basis, of symptoms of a mania, mixed mood disorder, or hypomania, despite an absence of obvious causative factors. Those obvious causative actors include developmental disability, toxicities, psychologic illnesses, and comorbid medical condtions (such as diabetes, heart failure, medications, endocrine illness, and discrete intracranial illnesses).
Although bipolar illness often can be found to have gentic correlates, its source, separate from familial and idiopathic genetics, is not known.
Evidence is accumulating that there are discrete environmental contributors such as diet and physical settings.